A behavioural task to determine the effects of sustained context-related inhibition during motor control

Background: Modulation of learned “motor programs“ is the basis of context-adequate behaviour, consisting of retrieval or non-retrieval (inhibition) of behavioural elements. Evidence was provided that focal activation/deactivation represents contextual modulation [1,2]. It remains open, whether context-related deactivation represents truly behaviourally relevant inhibition. During non-retrieval subjects do not perform a task, thus no behavioural measurement can be acquired. To determine the behavioural effect during non-retrieval we developed a behavioural task and tested it in healthy subjects (HS). Methods: 32…