Impact of intraoperative physiologic target localisation on outcome following subthalamic deep brain stimulation

Objective: To compare the outcome in two series of patients with Parkinson's disease (PD) treated by subthalamic deep brain stimulation (STN-DBS) either using intraoperative macrostimulation alone or multitrajectory microelectrode mapping (MMM). Background: The implantation of electrodes for STN-DBS requires intraoperative neurophysiological verification. This may be achieved by macrostimulation alone or by combined microrecording and -stimulation. There is a debate on the possible benefits and risks of MMM, but few available data. Methods: We retrospectively analysed 39 PD patients who received STN-DBS between…