Brain activation patterns during imagined locomotion in blind subjects

Objective: To investigate differential brain activation patterns during imagined locomotion in congenitally blind versus sighted subjects. Methods: Seven congenitally blind subjects imagined to walk and run during a functional magnetic resonance imaging (BOLD-fMRI) study. Imagined lying served as rest condition. Seven age- and gender-matched healthy sighted subjects served as a control group. Thirty-two transversal slices covered the whole supratentorial brain and most parts of the cerebellum. Data analysis was performed using SPM2. Group analyses and intergroup comparisons were calculated, and a significance th…