CHANGES IN THE TUMORSPECIFIC IMMUNE RESPONSE AFTER RFA

Aims: Radiofrequency Ablation(RFA) is a widely used therapy for unresectable small tumor lesion in the liver. In the last few years there had been several evidences, that RFA has adjunctive immunomodulatory side effects. Activated tumorspecific lymphocytes could be found in peripheral blood after RFA in an animal model and in human. In this study the longterm appearance of activated tumorspecific T cells after RFA should be proofed in human. Materials and Methods: 5 patients were enrolled to this study –3 patients suffering from colorectal cancer metastases to the liver(CRC) and 2 suffering from hcc. Blood was t…