Acute anxiolytic effects of a refined Valeriana officinalis extract in healthy humans

A new, patented, refined Valeriana officinalis extract (phytofin Valerian 368) from Finzelberg GmbH & Co. KG has previously been shown to possess anxiolytic properties in rodent models of anxiety [1]. The current study extended this line of research into humans. In this double-blind, placebo-controlled, crossover study, 29 healthy participants attended the laboratory on three separate days, 7 days apart, receiving a different treatment in counterbalanced order on each occasion (placebo, 300, 900mg valerian extract). On each day mood and physiological responses were assessed pre-dose and at 1 and 3 hours post-dos…