Synergy research: A new approach to the efficacy of multi herbal drug combinations in phytotherapy

Many years of therapeutic experience with herbal drug combinations have shown that they possess better efficacy and reduced side-effects in comparison with single herbal drugs. The same is also true of standardized plant mono-extracts as compared with single isolated constituents thereof. Detailed pharmacological investigations using molecular biological assays have revealed that this better efficacy must be due to additive or potentiated synergy effects caused by the constituents of the extract combinations. Several examples show how these synergy effects can be determined. Further information on mechanisms und…