False recognition correlates with β-Amyloid (1–42), but not with total Tau in CSF of patients with dementia or mild cognitive impairment

A severe Memory impairment forms the core symptom of Alzheimer's disease (AD) and precedes the clinical presentation of cognitive deterioration for several years. Recent studies show that Alzheimer patients not only suffer from forgetfulness, but also differ in their response bias when recognizing remembered and familiar information. Altered total Tau-protein and β-Amyloid (1–42) concentration in the CSF is also a well-known feature of AD and they predict a conversion to dementia in mild cognitive impaired patients. In this study we correlated recognition scores of neurological patients with memory impairments w…