Increased Renal Interlobar Vein Impedance Index in relation to clinical onset of pre-eclampsia

Aims: In a former study, we observed that Renal Interlobar Vein (RIV) Impedance Index (VI) – which is the Doppler equivalent of Arterial Resistance Index – was significantly higher in pre-eclampsia (PE) than in normal pregnancy, and that this could be linked to cardiovascular and renal haemodynamic maladaptation. Aims: To study time-relationship between increase of RIV VI and clinical onset of PE. Methods: Prospective evaluation of 25 women, at high risk for PE. All observations started when course of pregnancy was normal. Blood pressure, proteinuria and fetal growth were evaluated 1- to 4-weekly, together with…