Prenatal diagnosis of cleft lip in an epileptic pregnant

Upper lip and palate develop at the 6th week of gestation where insufficient fusion of the cleft lip and palate may occur. We report a case that was diagnosed prenatally with cleft lip A 29 year old woman with history of epilepsy under valproid acid was booked at 8 weeks of pregnancy. She was receiving folic acid. The fetus was diagnosed with unilateral cleft lip on a 3D/4D ultrasonography scan at 16 weeks of pregnancy. No malformation of the hard palate was identified. At 21 weeks the cleft lip was further studied with 3D ultrasonography which confirmed the previous findings. The fetal hard and soft palate were…