Discrepant results between routine screening for latent tuberculosis (TB) and Quantiferon® in patients with inflammatory bowel diseases (IBD)
P Papay, A Eser, P Paulinska, C Lichtenberger, A Mikulits, W Miehsler, C Dejaco, G Novacek, H Vogelsang, W Reinisch · Zeitschrift für Gastroenterologie · 2008 · Heft 06
Bibliografische Angaben
Zusammenfassung
Background/Aim: Screening for latent TB is part of the routine management in patients with IBD before starting therapy with any anti-Tumor Necrosis Factor (TNF)! compound. Recently, the whole blood interferon “ assay (QuantiFERON®) has been introduced as additional test to routine screening consisting of tuberculin skin test (TST) and chest X-ray. Our aim was to compare these diagnostic methods in consecutive IBD patients with the indication of anti TNF! therapy. Patients/Methods: To date, 78 patients with IBD, who started treatment with infliximab, adalimumab or certolizumab were screened for latent tuberculosi…
