Neurophysiological Evidence for Transcallosal Somatosensory Processing in Humans

Introduction: Interhemispheric information transfer is crucially dependent on the integrity of the corpus callosum (CC). It has been previously shown that the intactness of the posterior body of the CC is relevant for the performance of tactile behavioral tests, i.e. intermanual tasks of tactile finger localization (TFL) and haptic object recognition (HOR) tests. In this study, we aimed at providing neurophysiological evidence of transcallosal somatosensory processing (TCSP) for the first time. Methods: We investigated the effects of conditioning electrical stimuli (CS) applied to the left median nerve (MN) on c…