Calprotectin als Marker für gastrointestinale Erkrankungen bei Frühgeborenen mit einem Geburtsgewicht
A Jenke, P Wintermeyer, HJ Bittrich, T Frank, C Güttel, S Wirth · Klinische Pädiatrie · 2010 · Heft 06
Bibliografische Angaben
Zusammenfassung
Background: Necrotising enterocolitis (NEC) is the most common gastrointestinal emergency in neonates with high mortality and morbidity especially in very low birth weight infants (VLBW). Methods: In order to assess the suitability of fecal calprotectin levels as predictive marker for NEC in VLBW we started a prospective multi-centre study in May 2008. Up to September 2009, 227 patients were included with complete data available in 168 cases. The mean gestational age was 29.1 weeks (23.0–34.1) and mean birth weigt 1048g (354–1490g). 11 patients suffered from NEC defined as NEC-stage ≥ II (6.6%). 6 of those prese…