Association of ambient air pollution with blood markers of inflammation and coagulation: Results from a prospective panel study in Augsburg, Germany
I Brüske, R Hampel, R Rückerl, R Phipps, B Devlin, D Diaz-Sanchez, W König, J Cyrys, S Breitner, P Belcredi, A Peters, A Schneider · Das Gesundheitswesen · 2010 · Heft 09
Bibliografische Angaben
Zusammenfassung
Background: While there is compelling evidence that elevated concentrations of particulate matter are associated with cardiovascular disease exacerbation, the pathophysiological mechanisms remain unclear. Objective: To examine the effect of ambient air pollutants on blood markers of inflammation and coagulation in individuals with type 2 diabetes (T2DM) or impaired glucose tolerance (IGT) and in healthy people with a potential genetic predisposition on the detoxifying pathway. Materials and Methods: The study consisted of two panels of non-smoking individuals: 1) individuals with either T2DM (n=83) or IGT (n=104…