Gene-nutrition interactions that modify the risk of upper aero-digestive tract cancer. Screening results of a European multi-center case-control study
R Foraita, T Behrens, I Holcátová, D Conway, A Metspalu, A Znaor, P Lagiou, C Healy, L Simonato, R Talamini, F Merletti, M Hashibe, P Brennan, W Ahrens · Das Gesundheitswesen · 2010 · Heft 09
Bibliografische Angaben
Zusammenfassung
Introduction: Tobacco smoking and consumption of alcoholic beverages are established causes of cancers of the upper aero-digestive tract (UADT) and reduced intake of vegetables and fruits are likely causes. Little is known, however, about the role of gene-environment interactions (GEIs) respecting nutritional factors. Material and Methods: The study is embedded in the Alcohol-Related Cancers and Genetic Susceptibility in Europe (ARCAGE) study, a multi-centre case-control study conducted 2002–2005 in 10 European countries. Dietary habits were assessed using a semi-quantitative food frequency questionnaire. The an…