Prospective validation of a simple laboratory score to predict outcome after orthotopic liver transplantation

Aims: Early identification of patients with adverse outcome after liver transplantation remains difficult. The aim of the present study was to establish a score to predict 30 day mortality and graft loss retrospectively and to validate the score prospectively. Methods: Retrospectively, from 296 liver transplanted patients a score was developed that included peak-AST within the first week, gamma-GT at day 7 and bilirubin at day 7 to predict graft loss or patient death within 30 days. The score obtained was then prospectively validated in 86 patients undergoing liver transplantation. Results: From the retrospectiv…