The role of HDV in the natural history of the persistent HBV infection
B Calle Serrano, J Jaroszewicz, B Heidrich, J Grabowski, B Bremer, K Deterding, M Cornberg, MP Manns, H Wedemeyer · Zeitschrift für Gastroenterologie · 2011 · Heft 01
Bibliografische Angaben
Zusammenfassung
Introduction: The natural course of the persistent HBV infection is complex and dynamic with four main phases: immune-tolerance (IT), immune-clearance (IC), low-replicative/inactive-carrier (LR) and HBe-Antigen-negative hepatitis (ENH]. However, the role of HDV co-infection in the progression of the different phases of HBV infection is unclear. Methods: 52 patients with hepatitis delta were followed for up to 14 years (median 3.41 years). None of them was receiving therapy at baseline; along follow up, 22 patients remained untreated. The baseline characteristics of this delta co-infected group was compared with…
