Erhöhte Leptin-Werte bei sozial isolierten Männern mit depressiver Symptomatik – Leptin, ein Stressmarker bei Männern?
S Häfner, A Zierer, RT Emeny, B Thorand, C Herder, W Koenig, KH Ladwig · Psychotherapie Psychosomatik Medizinische Psychologie · 2011 · Heft 02
Bibliografische Angaben
Zusammenfassung
Leptin, involved in energy homeostasis and predictor of cardiovascular disease, has recently been recognized as mediator in stress response. We explored the association between leptin levels and two stress-related conditions, social isolation and depressed mood. We analysed leptin levels in 1,229 subjects, derived from the population-based MONIKA/KORA study. Standardized questionnaires were used to assess depressed mood and social isolation. In a multiple linear regression the association between leptin, social isolation and depressed mood and its interaction was explored in men and women separately. Leptin was…