Lateralized central facilitation of trigeminal nociception in cluster headache
D. Holle, C. Gaul, S. Krebs, S. Nägel, H.C. Diener, H. Kaube, Z. Katsarava, M. Obermann · Klinische Neurophysiologie · 2011 · Heft 03
Bibliografische Angaben
Zusammenfassung
Background: Central facilitation of trigeminal pain processing was demonstrated in different primary headache and facial pain disorders. Whether it is also part of the pathophysiology of cluster headache (CH) has been intensively discussed due to inconsistent study results. Methods: Sixty-six patients with CH (18 episodic CH inside bout, 28 episodic CH outside bout, 20 chronic CH) according to the ICHD-II-classification, as well as 30 healthy controls were investigated using simultaneous recordings of the nociceptive blink reflex (nBR) and pain related evoked potentials (PREP) following nociceptive electrical st…