Botulinum toxin (BoNT) in headache disorders
S. Silberstein · Aktuelle Neurologie · 2011 · Heft 04
Bibliografische Angaben
Zusammenfassung
Headache disorders, including migraine and chronic migraine (headaches ≥15 days/month and a link to migraine) are common debilitating conditions that profoundly impact quality of life. There are 7 BoNT serotypes (A, B, C1, D, E, F, and G). Botulinum toxin type A (BoNTA) has been the most widely studied serotype for therapeutic purposes. Several randomized, double-blind, placebo-controlled studies support the efficacy of BoNT for the treatment of chronic migraine. More recently, the PREEMPT clinical program confirmed OnabotulinumtoxinA as an effective, safe, and well-tolerated headache prophylactic treatment for…