Impact of a DPP4-inhibitor on liver and heart lipid content and cardiovascular risc in type 2 diabetic patients
L Kosi, M Chmelik, A Kautzky-Willer · Diabetologie und Stoffwechsel · 2011 · Heft 05
Bibliografische Angaben
Zusammenfassung
Aims: Increased liver and cardiac fat are common in patients with type 2 diabetes mellitus (T2DM) and associated with increased risc for liver fibrosis and cardiovascular events. The effect of a DPP-4 inhibitor on the fat content of the liver and heart has not been evaluated. Methods: 40 Patients, 20 male and 20 female, treated at our diabetes metabolic unit of the Medical University of Vienna with gliptins underwent magnetic resonance spectroscopy before and 6 months after start of therapy with a gliptin. MRT was performed with 3 Tesla Siemens MRT Results: 40 patients have been included, 10 patients have finish…