Immunoreactive score of Ep-CAM might predict survival in early ovarian cancer patients
MJ Battista, J Steetskamp, N Mantai, S Gebhard, C Cotarelo, A Victor, I Petry, M Schmidt, H Kölbl · Geburtshilfe und Frauenheilkunde · 2011 · Heft 08
Bibliografische Angaben
Zusammenfassung
Background: The epithelial cell adhesion molecule (Ep-CAM) is a well known adhesion molecule serving as a target for targeted therapies in ovarian cancer (OC) and prediction of breast cancer. Here, we studied a possible association between Ep-CAM expression and prognosis in patients with early OC. Material and Methods: All OC patients who were treated at our institution between the years of 1980 and 2003 with FIGO stage I-II, available follow-up information and OC tissue were enrolled in this study. Ep-CAM expression was assessed using an immunoreactive score defined by the product of a proportion and intensity…
