Tocolysis with Beta-2-sympathomimetics Increases the Occurrence of Infantile Hemangiomas in Preterm Born Infants

Ziel: Infantile hemangioma (IH) is the most commonly observed tumor in children. As recently detected, off-label pharmacological treatment of IH with the beta-blocker propranolol induces regression of IH. Based on the fact that IH are more frequently observed in premature babies than in mature babies and the evidence that beta-blocker therapy leads to regression of IH we generated the hypothesis that the use of betamimetics during pregnancy for inhibiting premature labor might increase occurrence of IH in preterm infants. Methodik: Data of 328 preterm infants (< 32 gestational weeks) or with a birth weight of le…