Comparison of therapy outcome of patients with drug addiction (DA) versus patients with former iv drug use (IVDU) treated with Peginterferon alfa–2a/Ribavirin in real life setting
S Mauss, D Hüppe, T Lutz, A Schober, G Moog, KH Hey, W Schiffelholz, G Teuber, A Baumgarten, W Schmidt, A Stoehr, M Waizmann, K Isernhagen, U Alshuth, P Buggisch · Zeitschrift für Gastroenterologie · 2012 · Heft 01
Bibliografische Angaben
Zusammenfassung
Aims: Small clinical trials showed that pts with former IVDU achieved lower SVR rates than patients under drug addiction. These results were explained by higher adherence and lower drop out rates of methadone substituted pts. Methods: From January 2008 to February 2011, 3793 patients with chronic HCV were documented in a German-wide non-interventional study (bng/Roche). 924 naive patients with completed documentation were stratified according to their history of former iv drug use (N=392) or recent drug addiction (N=532) during treatment against HCV. Results: Main baseline-characteristics of the population: age…