Electrophysiological changes of median nerve conduction (M-NC) after transsphenoidal surgery in acromegaly

Objective: Carpal tunnel syndrome (CTS) occurs frequently in patients with acromegaly. Aim of this study was to measure M-NC changes before and after transsphenoidal surgery of pituitary adenoma producing growth hormone in patients with acromegaly. Methods: Fifteen consecutively treated patients (30 hands) with acromegaly were clinically and electrophysiologically examined before, 1 week, 3 weeks, 3 months and one year after transsphenoidal resection of a growth hormone producing adenoma. Patients were examined endocrinologically and by MRI of the sella. Measurement of M-NC included distal motor (dml), sensory l…