Examining the response of primary Human Bronchial Epithelial Cells in an Air liquid interface culture system after stimulation with concentrated Exhaled Breath Condensate
R Muramatsu, J Koepke, M Dresel, A Hattesohl, G Hofmann, M Kauß, T Damm, T Greulich, C Vogelmeier, RA Koczulla · Pneumologie · 2012 · Heft 02
Bibliografische Angaben
Zusammenfassung
Introduction: Exhaled breath condensate (EBC) is a noninvasive method to analyze inflammatory mediators present in the lower respiratory system. EBC contains aerosolized particles reflecting the airway lining fluid with variations of mediators from different lung diseases. However there are limitations to EBC measurements due to the low concentration of proteins and biomarkers. In different lung diseases, such as alpha-1 antitrypsin deficiency (AATD), chronic obstructive pulmonary disease (COPD) and asthma, proteins and cytokines represented in air liquid interface (ALI) system after EBC stimulation are expected…
