High clarithromycin and levofloxacin resistance in Helicobacter Pylori strains isolated from patients in our high-volume academic endoscopic centre

Background: The antibiotic susceptibility is the cornerstone for the eradication strategies of Helicobacter pylori (H. pylori). Aims: To investigate the prevalence of primary antibiotic resistance of H. pylori in our academic centre. Methods: H. pylori isolates were obtained from consecutive patients submitted to gastroscopy for the evaluation of upper gastrointestinal symptoms. Biopsies from antrum and corpus were taken to determine the antibiotic susceptibility of H. pylori isolates. The minimal inhibitory concentration for amoxicillin, tetracycline, clarithromycin, metronidazole, rifabutin and levofloxacin we…