Prognostic serum biomarkers for graft survival after liver transplantation in hepatitis C patients
P Fytili, C Brauner, D Wenzel, AA Negm, A Gronert, H Barg-Hock, F Lehner, M Cornberg, MP Manns, C Falk, H Wedemeyer · Zeitschrift für Gastroenterologie · 2013 · Heft 01
Bibliografische Angaben
Zusammenfassung
Background and aims: Graft reinfection in liver transplanted patients with chronic hepatitis C (HCV) is almost universal leading to severe fibrosis and graft loss in 25–35% of the patients in the first five years after transplantation. As the currently available antiviral therapy is associated with severe side effects and rejection episodes, prognostic factors that can identify patients at risk for graft dysfunction and graft loss are urgently needed. We hypothesized that distinct immunological markers may predict the long-outcome of graft hepatitis C. Methods: Seventy-one HCV patients that underwent LTx in our…
