Serum protein biomarkers for acute rejection in liver transplantation
N Raschzok, KA Prabowo, A Reutzel-Selke, RB Schmuck, MH Morgul, LM Tannus, S König, S Jonas, P Neuhaus, IM Sauer · Zeitschrift für Gastroenterologie · 2013 · Heft 01
Bibliografische Angaben
Zusammenfassung
Introduction: Although 20–40% of patients experience at least one episode of acute rejection (AR) after liver transplantation (LTx), diagnosis of AR is still mainly based on tissue analysis from liver biopsies. Biomarkers in routinely taken blood samples would be a powerful non-invasive tool for monitoring of the liver graft status. The aim of this study was to investigate the diagnostic and prognostic value of serum protein biomarkers for acute rejection in LTx recipients. Methods: Serum samples were collected from patients undergoing LTx in a prospective clinical trial in two study centers (Leipzig and Berlin)…
