Gender and HLA type specific relapse rates in patients with autoimmune hepatitis
F Staib, S Fritzsche, A Jahn-Eimermacher, H Binder, A Gerhold-Ay, AP Barreiros, S Kanzler, M Müller, PR Galle, A Teufel · Zeitschrift für Gastroenterologie · 2013 · Heft 08
Bibliografische Angaben
Zusammenfassung
Aims: Autoimmune hepatitis (AIH) mostly affects women. The only available study on gender differences in risks to relapse reported a higher risk to relapse in men. However, this study did not reflect on the risk of multiple relapses. Furthermore, only little is known about seasonal contribution, e.g. by rate of viral infections, the role certain autoantibodies or HLA haplotypes in these gender differences, relapse rate, or prognosis. Methods: We reviewed a large Northern Europe cohort of 306 Patients, 256 female and 50 male. For statistical analysis of the influence of gender and HLA haplotypes on relapse rates,…
