Insulin resistance in women after pregnancy is associated with changes in the serum nonesterified fatty acid profile
M Fugmann, C Hellmuth, O Uhl, J Demmelmair, B Koletzko, U Ferrari, F Banning, V Sacco, S Heinrich, N Kammer, H Hetterich, K Parhofer, J Seißler, A Lechner · Diabetologie und Stoffwechsel · 2014 · Heft 05
Bibliografische Angaben
Zusammenfassung
Nonesterified fatty acids (NEFAs) play a major role in the pathophysiology of insulin resistance (IR), which can lead to type 2 diabetes. However, the importance of different NEFA species in early IR is unknown. Our aim was to study the relationship between NEFA profiles during an oral glucose tolerance test (oGTT) and IR in normoglycemic individuals. We examined insulin resistant women after gestational diabetes (IR-pGDM, n = 20) and insulin sensitive women after normoglycemic pregnancy (IS-NORM, n = 20) by an oGTT. Serum samples at 0 and 90 minutes were analyzed for qualitative and quantitative measurements of…
