Core/Shell electrospun fibers as biodegradable scaffolds for sustained drug delivery in Wound Healing applications
A Repanas, H Zernetsch, B Glasmacher · Pneumologie · 2014 · Heft 06
Bibliografische Angaben
Zusammenfassung
Aim: During the process of wound healing it is really important to keep the area safe from bacteria infections and treat possible inflammation incidents. Model antiseptic and anti-inflammatory agents can be encapsulated into a drug delivery carrier for combined treatment. Electrospinning (E-Spin) has been acknowledged as a versatile technique for the production of biodegradable fibrous scaffolds to encapsulate therapeutics for wound healing. Methods: Both single jet and coaxial jet E-Spin were used as a method to produce fibers. Polycaprolactone (PCL), Benzoin (BZ) and Acetyl Salicylic Acid (ASA) were dissolved…