Duration of remission and interpretation of biochemical markers within the normal range help to identify patients with high chance for sustained remission after treatment withdraw…

Aims: In autoimmune hepatitis (AIH), relapse rates as high as 95% have been reported after treatment withdrawal. We therefore investigated, whether longer duration of treatment and proper patient selection could increase the long-term success rates of treatment withdrawal. Methods: Following our previously published experience, treatment withdrawal was considered when biochemical remission was maintained under immunosuppressive monotherapy for at least 2 years. Remission was defined as repeatedly normal serum aminotransferase levels as well as normal IgG levels. Statistical analysis was performed by using cox re…