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Irisin expression in subcutaneous adipose tissue in obese patients with type 2 diabetes increases one year after bariatric surgery

A Harger, J Münzker, A Tuca, L Lindheim, V Zachhuber, B Obermayer-Pietsch, J Fruhmann, O Freisinger, F Tadler, E Svehlikova, TR Pieber · Diabetologie und Stoffwechsel · 2015 · Heft 04

Dokument
1021773
CareLit-ID
Jahr
2015
Publikation
PDF
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Metadaten
DOI
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Bibliografische Angaben

Zeitschrift
Diabetologie und Stoffwechsel
Autor:innen
A Harger, J Münzker, A Tuca, L Lindheim, V Zachhuber, B Obermayer-Pietsch, J Fruhmann, O Freisinger, F Tadler, E Svehlikova, TR Pieber
Ausgabe
Heft 04 / 2015
Seiten
–
Erschienen: 2015-04-29 00:00:00
ISSN
1861-9002
DOI
10.1055/s-0035-1549524

Zusammenfassung

Aim: Gastric bypass surgery improves glycaemic control, but the underlying mechanisms including potential changes in adipoinsular axis are incompletely understood. The aim of this study was to investigate potentially causal or associated alterations in gene expression of adipokines, myokines and hormones in the subcutaneous and visceral adipose tissue of diabetic and non-diabetic obese subjects before and after gastric bypass. Material and methods: Biopsy specimens from the subcutaneous adipose tissue of 12 diabetic and 12 non-diabetic patients at and one year after gastric bypass were analyzed with quantitative…

Schlagworte

Diabetologie und Stoffwechsel