Quantitative dual-energy computed tomography (DECT) imaging: Evaluation of system performance regarding iodine quantification accuracy

Purpose: Study purpose was the rigorous evaluation of the accuracy and stability of iodine quantification 'free-in-air' as well as in a body phantom in dependence of measurement position for different DECT acquisitions and reconstruction settings. Methods: Using a dual-source DECT system for iodine concentrations in the range of 0.0 – 15.0 mg/ml have been assessed for three DECT acquisitions (80/140 kVp, 80/Sn140 kVp, 100/Sn140 kVp) and two reconstruction kernels (D30f, D33f). Evaluation of iodine concentration quantification was performed using two experimental setups: 'Free-in-air' at the field-of-view center…