Neural correlates of reward processing and response inhibition in disordered gambling: The role of depressive symptomatology

Introduction: Cognitive features that play an important role in the development and maintenance of disordered gambling (DG) are impulsivity and sensitivity to reward. However, behavioural and neuroimaging findings are less consistent as one would expect when looking at the diagnostic criteria of the disorder. Given that almost half of the DGs suffer from comorbid depressive symptomatology our aim was to assess its impact on reward processing and response inhibition. Methods: We presented two different tasks during 3 tesla functional magnetic resonance imaging to study the neurobiological correlates of 1) effort-…