Natural course and prognostic factors in patients with cholestatic liver disease – experience from a single center study

Background and Aims: Primary biliary cholangitis (PBC) and primary sclerosing cholangitis (PSC) are the most common cholestatic liver diseases. However, the clinical course of PBC and PSC differs significantly among individuals and therefore scores using disease-specific parameters are necessary to identify patients who are at high risk developing complications with impaired prognosis. The aim of our study was to analyze the typical characteristics of patients with PSC and PBC focusing on treatment, prognostic factors and the prognostic significance of the recently established albumin-bilirubin (ALBI) score. Met…