Helicobacter pylori infection and small intestinal bacterial overgrowth

Introduction: H. pylori is a remarkable bacterium, because it has one of the highest urease activities of all known bacteria. Since H. pylori infection may increase the intra-gastric pH due to the production of ammonia, this bacterium may be a causative agent of small intestinal bacterial overgrowth (SIBO). The purpose of the present study was to investigate the presence of small intestinal bacterial overgrowth (SIBO) in patients with active H. pylori infection assessed by functional breath testing. Patients and Methods: All in all 109 patients with gastrointestinal complaints, who were referred for the H. pylor…