Decrease of Hyperferritinemia in chronic Hepatitis C patients due to IFN/RBV free antiviral treatment
R Stern, K Kozbial, C Freissmuth, S Beinhardt, A Stättermayer, P Munda, P Ferenci, H Hofer · Zeitschrift für Gastroenterologie · 2016 · Heft 05
Bibliografische Angaben
Zusammenfassung
Background: Elevated serum ferritin levels are common in patients with chronic HCV patient with advanced liver fibrosis and predictive for poorer response to treatment with pegylated interferon (PEG) and ribavirin (RBV). The aim of this study was to determine the effect of IFN/RBV free direct acting antiviral therapy on serum ferritin during and after antiviral treatment. In addition the association of serum ferritin with liver fibrosis was evaluated. Methods: 97 patients with chronic hepatitis C (median age: 56a (34 – 77) male: 83.6%) treated with interferon free DAA regimens (sovaldi combined either with dacla…