Colonization and infection with carbapenem-resistant non-fermenting gram-negative bacteria are associated with rapid deterioration and mortality in patients with decompensated liv…

Background: Bacterial infections are frequent complications in patients with advanced liver disease and impair their prognosis. The number of infections with multi-drug resistant gram-negative bacteria (MRGN) is rapidly increasing. Especially the occurrence of carbapenem resistant gram-negative bacteria (CRGN) narrows the therapeutic options. This study investigated the impact of CRGN on the outcome of patients with liver diseases, and aimed to identify pathogens causing adverse courses in these patients. Methods: We identified n = 132 liver patients in whom, whilst being treated at a tertiary liver transplant c…