Rapid and sustained improvements of liver stiffness values in HCV-infected patients treated with direct-acting antiviral drugs
D Attia, K Deterding, J Cornberg, MP Manns, M Gebel, M Cornberg, H Wedemeyer, A Potthoff · Ultraschall in der Medizin - European Journal of Ultrasound · 2016 · Heft 08
Bibliografische Angaben
Zusammenfassung
Background: The use of interferon-free antiviral therapy in patients with chronic HCV infection is associated with high rate of sustained virological response (SVR). The aim of this study was to evaluate changes of liver stiffness (LS) using Acoustic Radiation Force Impulse Imaging (ARFI) elastography and transient elastography (TE) during antiviral treatment and to evaluate its role in relation to SVR. Patients and methods: In total 337 chronic HCV-infected patients (mean age 59 years, 42% females) were included in this prospective single center study. Genotype 1 accounted for 75%, 244 patients (72%) had liver…
