Evaluation of liver fibrosis using Transient Elastography in non-alcoholic steatohepatitis (NASH) patients

Purpose: The purpose of this study was to assess by Transient Elastography (TE) the severity and dynamics of liver fibrosis in NASH patients. Material and methods: We conducted a prospective study on 890 NASH patients, diagnosed based on: ultrasound examination (“bright liver” with posterior attenuation); biological tests (increased aminotransferases level); no history of alcohol abuse; negative viral hepatitis B or C markers. In each patient ten liver stiffness measurements (LSM) were performed, either with M (3.5 MHz) or XL (2.5 MHz) probe. Reliable measurements were defined as: median value of 10 LSM with a s…