CareLit Fachartikel
Ein In-vitro-Mausmodell für die Palatogenese und die Entstehung von Gaumenspalten
N.N. · Informationen aus Orthodontie & Kieferorthopädie · 2017 · Heft 02 · S. 148-152
Dokument
1025525
CareLit-ID
Jahr
2017
Publikation
PDF
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Metadaten
DOI
ja
zitierfähig
Bibliografische Angaben
Zusammenfassung
Abstract The mouse is an excellent model to study palatogenesis since, like humans, it is a mammal, it can easily be bred and a wide array of molecular tools are available. Moreover, the isolated embryonic mouse palate can be cultured in vitro, which allows us to study the actual fusion process in detail. Just prior to the actual fusion at E13, the maxilla with the 2 palatal shelves can be dissected from the embryo head. The maxilla is cultured on a filter paper on top of a stainless-steel grid at the interface of the culture medium and air. After 24 h in culture, the palatal shelves are in contact and the MES i…
Schlagworte
Gaumenspalte
Embryologie
Maus
In-vitro-Verfahren
cleft palate
embryology
mouse
in vitro techniques
Lead
After
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