Functional MRI Activation of Mesial and Anterior Temporal Lobe Structures in TLE
K Franke, M Schacher, M Mertens, H Jokeit, OW Witte, A Ebner, B Pohlmann-Eden, F Wörmann · Klinische Neurophysiologie · 2004 · Heft 08
Bibliografische Angaben
Zusammenfassung
Background: The diagnostic procedure in temporal lobe epilepsy (TLE) and especially presurgical planning requires knowledge about the functional integrity of the areas to be resected. The mesial and anterior temporal lobe (TL) in humans are highly important in emotional, visual and memory processing. The amygdala itself is involved in the perception of emotional facial expression, particularly for fear. Methods: A new visual paradigm presenting animated fearful faces from movie scenes in alternation with landscape scenes was investigated using functional MRI. As a first step 12 healthy subjects (mean age 35 year…