Positron Emission Tomography in Psychiatric Research
G Gründer · Klinische Neurophysiologie · 2004 · Heft 08
Bibliografische Angaben
Zusammenfassung
Since the first visualization and quantification of D2 dopamine receptors with positron emission tomography (PET), nuclear imaging technology with PET and single photon emission computed tomography (SPECT) has led to an enormous gain in knowledge about the neurobiology and treatment of psychiatric disorders. With the development of selective high-affinity tracers for a large variety of neurotransmitter receptors and other targets such as enzymes it became possible to study normal and pathological neurochemistry in vivo in the human brain. In neuropsychopharmacology, PET led to a profound understanding of the rel…