Hirnaktivität beim Stehen, Gehen und Laufen bei vestibulär defizienten Patienten und gesunden Kontrollpersonen: Eine fMRT-Studie

Posture and gait are sensorimotor actions that involve peripheral, spinal, and supraspinal structures. To investigate brain activity during stance and locomotion, 13 healthy subjects and 7 patients with neurofibromatosis type II and complete vestibular loss due to chronic bilateral neurectomy for acoustic neurinoma were asked to stand, walk, run, and lie down; subsequently they were trained to imagine standing, walking, running, and lying (imagined lying as rest condition in fMRI). In healthy subjects separate and distinct activation/deactivation patterns were found for the three imagined conditions: (1) standin…