Expression of Augmenter of Liver Regeneration in Human Liver Cirrhosis and Carcinoma
WE Thasler, T Schlott, P Thelen, C Hellerbrand, F Bataille, M Lichtenauer, HJ Schlitt, KW Jauch, TS Weiß · Zeitschrift für Gastroenterologie · 2005 · Heft 01
Bibliografische Angaben
Zusammenfassung
Aims: Recently, a protein termed “Augmenter of Liver Regeneration“ (ALR) was found to have a specific and beneficial effect on the proliferation of damaged liver tissue. It was proposed that ALR, as a member of hepatotrophic growth factors might act through auto- and paracrince mechanism during liver regernation, but little is known about its expression in normal and diseased human liver. Methods and Results: ALR expression in normal (n=18) and cirrhotic livers (n=25) with various underlying diseases as well as in tissue samples of hepatocellular carcinoma (HCC) (n=9) and cholangiocellular carcinoma (CCC) (n=5)…
