Molecular biologocal relevances of metal element concentrations during hepatic ischaemia-reperfusion

Introduction Ischaemia-reperfusion is considered as one of the main risk factors during operations on the liver. The presence of oxidative stress is well known in the literature. Our aim was to elucidate the connection between the alterations of metal element concentrations and the redox defensive system. Methods Wistar rats were divided into control, sham operated (S), ischaemic and reperfusion (R) groups. Hepatic ischaemia was induced for 45 minutes, which was followed by 15 minutes of reperfusion. Metal concentrations of the liver were determined with ICP-OES. H-donating ability (HDA), reducing power (RP), TA…