PREDICTION OF EARLY CHEMOTHERAPY-RESPONSE IN PRIMARY BREAST CANCER BY DOPPLER ULTRASOUND

Problemstellung: Primary systemic chemotherapy became a widely used approach in breast cancer treatment. In this setting tumor response is a major focus of interest. Tumor growth and regression are directly correlated to tumor vascularisation, which can be assessed by Doppler ultrasound. We hypothesized that breast cancer vascularisation changes under chemotherapy. We analyzed if Doppler-ultrasound is the favorable method to detect tumor response over measurement of tumor size by regular ultrasound. Methoden: 21 patients with histologically confirmed breast cancer and treatment by primary systemic chemotherapy w…