CareLit Fachartikel

Whole-body high-field magnetic resonance imaging in myotonic dystrophy type 1 and type 2

C Kornblum, R Schröder, K Kesper, T Klockgether, H Schild, G Lutterbey, M Wattjes · Aktuelle Neurologie · 2005 · Heft 10

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1040288
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Jahr
2005
Publikation
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Bibliografische Angaben

Zeitschrift
Aktuelle Neurologie
Autor:innen
C Kornblum, R Schröder, K Kesper, T Klockgether, H Schild, G Lutterbey, M Wattjes
Ausgabe
Heft 10 / 2005
Seiten
–
Erschienen: 2005-10-26 00:00:00
ISSN
0302-4350
DOI
10.1055/s-2005-919435

Zusammenfassung

Background: The aim of the present study was to determine if whole-body high-field Magnetic Resonance Imaging (MRI) techniques may identify characteristic patterns of skeletal muscle affection and subclinical skeletal muscle involvement in Myotonic Dystrophy Type 1 (DM1) and Type 2 (DM2). Methods: 15 DM1 (5m/10f; mean age 46+/-15 y) and 14 DM2 pat. (8m/6f; mean age 52+/-12 y) were studied by whole-body MRI of 3.0 T using a standard body coil and flexible table top extension (transversal slices, T1 TSE, T2 TSE, T2 TSE SPAIR). Skeletal muscle signal changes were graded on a 3 point scale. Clinical muscular impairm…

Schlagworte

Aktuelle Neurologie