Fast whole brain T1 mapping at 3 Tesla

Purpose: The purpose of this work is to obtain a fast method for T1 relaxation time measurements at 3 Tesla. Methods: The schematic pulse sequence diagram shown in figure 1 is implemented on a Philips 3T intera scanner. The method is a variation on the methods published by Ordigde et al. [1] and Clare & Jezzard. [2]. Figure 1 After a global inversion pulse a single shot EPI sequence with 60 slices is used to sample the inversion recovery curve. The first slice is acquired at TI=20 ms after the inversion pulse. The slice to slice timing DT=60 ms. At the next repetition of the sequence, the order in which the slic…